Lenalidomide-acetylene-C5-COOH
Lenalidomide-acetylene-C5-COOH(compound43;Cereblonligand-linkerConjugate)是一种基于Lenalidomide的，可募集CRBN蛋白的Cereblon配体。可通过linker与靶蛋白配体连接，形成PROTAC分子。
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包装价格促销价数量
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100mg￥17100.0013680.00- +
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500mg￥41675.0033340.00- +
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- 货号: ajcx30904
- CAS: 2429878-72-6
- 别名: Cereblon ligand-linker Conjugate
- 分子式: C21H22N2O5
- 分子量: 382.41
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-acetylene-C5-COOH can be connected to the ligand for protein by a linker to form PROTAC[1].
[1]. Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.
