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- Angiotensin-converting Enzyme (ACE)
- m-PEG5-NHS ester
m-PEG5-NHS ester
m-PEG5-NHSester是一种基于PEG的PROTAClinker，可用于PROTAC的合成。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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250mg￥1850.001480.00- +
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500mg￥3100.002480.00- +
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- 货号: ajcx31106
- CAS: 874208-94-3
- 别名: 甲基-四聚乙二醇-丙烯酸琥珀酰亚胺酯
- 分子式: C16H27NO9
- 分子量: 377.39
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
m-PEG5-NHS ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67.
