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NSC15364是一种VDAC1寡聚化和细胞凋亡(apoptosis)抑制剂。
NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1].
Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis[1].
[1]. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.
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