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PfDHODH-IN-2

PfDHODH-IN-2, a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (pfDHODH) inhibitor with an IC50 of 1.11 ?M, acting as an antimalarial agent which can be used for the research of malaria.

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PfDHODH-IN-2的二维码
  • 库存: 现货
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  • 5mg
    ¥1850.00
    1480.00
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  • 10mg
    ¥2825.00
    2260.00
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  • 25mg
    ¥5287.00
    4230.00
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  • 50mg
    ¥8200.00
    6560.00
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  • 100mg
    ¥11337.00
    9070.00
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  • 货号: ajcx31284
  • CAS: 425629-94-3
  • 别名: 2-[((4-氯苯基)氨基]-4-氧代-4,5-二氢噻吩-3-羧酸乙酯
  • 分子式: C13H12ClNO3S
  • 分子量: 297.76
  • 纯度: >98%
  • 溶解度: DMSO: 12.5 mg/mL (41.98 mM); Water: < 0.1 mg/mL (insoluble)
  • 储存: Store at -20°C
  • 库存: 现货

Background

PfDHODH-IN-2, a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (pfDHODH) inhibitor with an IC50 of 1.11 ?M, acting as an antimalarial agent which can be used for the research of malaria.


[1] Xu M, et al. J Med Chem. 2013 Oct 24;56(20):7911-24.

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