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PfDHODH-IN-2, a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (pfDHODH) inhibitor with an IC50 of 1.11 ?M, acting as an antimalarial agent which can be used for the research of malaria.
PfDHODH-IN-2, a dihydrothiophenone derivative, is a potent Plasmodium falciparum dihydroorotate dehydrogenase (pfDHODH) inhibitor with an IC50 of 1.11 ?M, acting as an antimalarial agent which can be used for the research of malaria.
[1] Xu M, et al. J Med Chem. 2013 Oct 24;56(20):7911-24.
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