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PhysalinF是一种具有强烈抗炎和免疫调节作用的分泌型甾体。PhysalinF诱导人外周血单个核细胞凋亡,降低人T淋巴细胞1型病毒(HTLV-1)感染后的自发增殖和细胞因子的产生。
Physalin F is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBMC, decreasing the spontaneous proliferation and cytokine production caused by Human T-lymphotropic virus type 1 (HTLV-1) infection[1].
Physalin F is a seco-steroid from Physalis angulate L.[1].
[1]. Pinto LA, et al. Physalin F, a seco-steroid from Physalis angulata L., has immunosuppressive activity in peripheral blood mononuclear cells from patients with HTLV1-associated myelopathy. Biomed Pharmacother. 2016;79:129-134.
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