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- E3 Ligase Ligand-Linker Conjugate
- Pomalidomide-PEG3-C2-NH2 TFA
Pomalidomide-PEG3-C2-NH2 TFA
Pomalidomide-PEG3-C2-NH2TFA是一种合成的E3连接酶配体-linker偶联物，包含基于Pomalidomide的cereblon配体和3个单元PEG的linker。
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包装价格促销价数量
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100mg￥3775.003020.00- +
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500mg￥14425.0011540.00- +
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1g￥26712.0021370.00- +
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2g￥37400.0029920.00- +
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- 货号: ajcx31328
- CAS: 2414913-97-4
- 别名: 沙利度胺-NH-PEG3-NH2TFA,Cereblon Ligand-Linker Conjugates 5 TFA; E3 ligase Ligand-Linker Conjugates 30 TFA
- 分子式: C23H29F3N4O9
- 分子量: 562.49
- 纯度: ＞98%
- 溶解度: DMSO: 100 mg/mL (177.78 mM); Ethanol: 100 mg/mL (177.78 mM); Water: 16.67 mg/mL (29.64 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
Pomalidomide-PEG3-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
[1]. Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.
