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  • PTP1B-IN-9
PTP1B-IN-9的可视化放大

PTP1B-IN-9

An inhibitor of the ubiquitin-proteasome system

原价
￥987-4525
价格
￥ 790-3620
PTP1B-IN-9的二维码

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  • 库存: 现货
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  • 货号: ajcx31362
  • CAS: 145888-79-5
  • 别名: NSC 638643
  • 分子式: C19H13Cl4NO
  • 分子量: 413.12
  • 纯度: >98%
  • 溶解度: DMSO: 5 mg/mL (12.10 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

RAMB4 is an inhibitor of the ubiquitin-proteasome system.1 It increases the levels of polyubiquitinated proteins in HeLa cervical cancer cells, but does not inhibit the chymotrypsin-like, trypsin-like, or peptidylglutamyl peptide hydrolyzing-like activities of the 20S proteasome, in cell-free assays when used at a concentration of 10 ?M. RAMB4 decreases the viability of HeLa cells (IC50 = 2 ?M).


1.Anchoori, R.K., Khan, S.R., Sueblinvong, T., et al.Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cellsPLoS One6(8)e23888(2011)

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