SP-8356
SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.
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包装价格促销价数量
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5mg￥4525.003620.00- +
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10mg￥7550.006040.00- +
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50mg￥20300.0016240.00- +
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100mg￥32062.0025650.00- +
- 货号: ajcx31488
- CAS: 1454885-45-0
- 别名:
- 分子式: C18H20O4
- 分子量: 300.35
- 纯度: ＞98%
- 溶解度: DMSO: 100 mg/mL (332.94 mM)
- 储存: Store at -20°C
- 库存: 现货
Background
SP-8356, an anti-inflammatory synthetic verbenone derivative, is a CD147 inhibitor with respect to its regulation of breast cancer cell behavior and cancer progression.
SP-8356, a synthetic anti-inflammatory verbenone derivative, exerts remarkable anti-atherosclerotic effects through inhibiting CD147-CypA interactions and reducing CypA-induced MMP-9 activation and monocyte adhesion.[2]
SP-8356 suppresses collagenase activity, MMP-9, and CypA, preventing the formation of plaque and attenuates its vulnerability in mice models of atherosclerosis.[2]
[1] Pahk K, et al. J Transl Med. 2019 Aug 20;17(1):274. [2] Pahk K, et al. Int J Mol Sci. 2019 Dec 21;21(1):95.
