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Terazosindimerimpuritydihydrochloride是Terazosin的二聚体,也是Terazosin的杂质。Terazosin是喹唑啉衍生物,是竞争性的,具有口服活性的α1-肾上腺素(α1-adrenoceptor)受体拮抗剂。
Terazosin dimer impurity dihydrochloride, a dimer of Terazosin, is an impurity of Terazosin. Terazosin is a quinazoline derivative and a competitive and orally active α1-adrenoceptor antagonist[1].
[1]. Michel MC, et al. Drugs for treatment of benign prostatic hyperplasia: affinity comparison at cloned alpha 1-adrenoceptor subtypes and in human prostate. J Auton Pharmacol. 1996 Feb;16(1):21-8.
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