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- Bcl-2 Family
- Venetoclax N-oxide
Venetoclax N-oxide
VenetoclaxN-oxide是Venetoclax的杂质。Venetoclax(ABT-199;GDC-0199)是一种高效，选择性的和口服有效的Bcl-2抑制剂，Ki小于0.01nM。
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包装价格促销价数量
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5mg￥3775.003020.00- +
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10mg￥5937.004750.00- +
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- 货号: ajcx31644
- CAS: 2469279-00-1
- 别名:
- 分子式: C45H50ClN7O8S
- 分子量: 884.44
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
Venetoclax N-oxide is an impurity of Venetoclax. Venetoclax (ABT-199; GDC-0199) is a highly potent, selective and orally bioavailable Bcl-2 inhibitor with a Ki of less than 0.01 nM[1].
[1]. Souers AJ, et al. ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets. Nat Med. 2013 Feb;19(2):202-8.
