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  2. Angiotensin-converting Enzyme (ACE)
  3. Methyltetrazine-acid
  • Methyltetrazine-acid
Methyltetrazine-acid的可视化放大

Methyltetrazine-acid

Methyltetrazine-acid是一种PROTAClinker，属于alkylchain类。可用于合成PROTAC分子。

原价
￥812-1962
价格
￥ 650-1570
Methyltetrazine-acid的二维码

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  • 库存: 现货
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  • 货号: ajcx31724
  • CAS: 1380500-88-8
  • 别名:
  • 分子式: C11H10N4O2
  • 分子量: 230.22
  • 纯度: >98%
  • 溶解度: DMSO: 100 mg/mL (434.37 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Methyltetrazine-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].


PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].


[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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