A coccidiostat
Nicarbazine is a coccidiostat.1 It is composed of an equimolar complex of 4,4'-dinitrocarbanilide (DNC) and 2-hydroxy-4,6-dimethylpyrimidine (HDP). Nicarbazine (0.01-0.04% in the diet) prevents mortality of, and suppresses oocyst production in, chickens infected with the parasites E. acervulina, E. necatrix, E. tenella, and P. gallinaceum. Dietary administration of nicarbazine (100 ppm) decreases the production, weight, and pigmentation of eggs produced by broiler breeder chickens.2 Formulations containing nicarbazine have been used in the prevention of coccidiosis in chickens.
1.Ott, W.H., Kuna, S., Porter, C.C., et al.Biological studies on nicarbazin, a new anticoccidial agentPoult. Sci.35(6)1355-1367(1956) 2.Hughes, B.L., Jones, J.E., and Toler, J.E.Effects of exposing broiler breeders to nicarbazin contaminated feedPoult. Sci.70(3)476-482(1991)
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