DBCO-PEG4-Maleimide

DBCO-PEG4-Maleimide是一种可降解(cleavable)的ADClinker，用于抗体偶联药物(ADCs)的合成。

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Background

DBCO-PEG4-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[1]. Xiaotian Zhong, et al. Capped and uncapped antibody cysteines, and their use in antibody-drug conjugation. WO2017025897A2.

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