β-Casomorphin,humanTFA(Humanβ-casomorphin7TFA)是一种阿片样肽,作为opioid受体激动剂。
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β-Casomorphin, human TFA (Human β-casomorphin 7 TFA) is an opioid peptide, acts as an agonist of opioid receptor[1][2].
β-Casomorphin, human TFA induces contractions of the guinea-pig ileum myenteric plexus/longitudinal muscle preparation with an IC50 of 29 μM[1].β-Casomorphin, human TFA displaces 3H-spiperone from receptors in frontal cortex starting with 500 nM concentrations[2].
[1]. Brantl V. Novel opioid peptides derived from human beta-casein: human beta-casomorphins. Eur J Pharmacol. 1984 Oct 30;106(1):213-4. [2]. Koch G, et al. Opioid activities of human beta-casomorphins. Naunyn Schmiedebergs Arch Pharmacol. 1985 Dec;331(4):351-4.
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