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安捷凯生物医药，安捷凯化学
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  2. FAK (Focal Adhesion Kinase or PTK2)
  3. MID-1
  • MID-1
MID-1的可视化放大

MID-1

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction, which can disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevate

原价
￥1737-10687
价格
￥ 1390-8550
MID-1的二维码

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  • 库存: 现货
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  • 货号: ajcx31922
  • CAS: 312608-54-1
  • 别名:
  • 分子式: C12H11N3O4S
  • 分子量: 293.3
  • 纯度: >98%
  • 溶解度: DMSO: 31.25 mg/mL (106.55 mM)
  • 储存: Store at -20°C
  • 库存: 现货

Background

MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction, which can disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.


[1] Lee H, et al. J Biol Chem. 2016 Dec 23;291(52):26627-26635.

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