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(S,R,S)-AHPC-PEG5-Boc是一种E3连接酶配体-linker偶联物(E3ligaseligand-linkerconjugate),包含基于(S,R,S)-AHPC的VHL配体和1个linker。用于合成Cdc20降解剂CP5V。
(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V[1].
[1]. Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.
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