Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer
Trans-Chalcone, the backbone of flavonoids, also is a potent fatty acid synthase (FAS) with IC50 of 17.1 μg/mL, and α-amylase inhibitor, causes cellcycle arrest and induces apoptosis in the breastcancer cell line MCF-7, exerting antifungal and anticancer activities.
[1] Bitencourt TA, et al. BMC Complement Altern Med. 2013 Sep 17;13:229. [2] Najafian M, et al. Mol Biol Rep. 2011 Mar;38(3):1617-20. [3] Bortolotto LF, et al. Biomed Pharmacother. 2017 Jan;85:425-433.
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