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Metronidazole acetic acid 是 Metronidazole 的代谢产物,在细菌中具有诱变活性。Metronidazole 是一种硝基咪唑类抗生素,杀螨剂和抗原生动物剂,特别用于厌氧细菌和原生动物。
Metronidazole acetic acid is a metabolite of Metronidazole with mutagenic activity in bacteria. Metronidazole is a nitroimidazole antibiotic, amebicide, and antiprotozoal agent used particularly for anaerobic bacteria and protozoa[1][2][3].
[1]. M Chacko, et al. Studies on the Possible Mutagenic Action of Metronidazole. Indian J Exp Biol. 1987 Apr;25(4):240-3.
[2]. M D Mudry, et al. Mutagenic Bioassay of Certain Pharmacological Drugs: III. Metronidazole (MTZ). Mutat Res. 1994 Mar 1;305(2):127-32.
[3]. In Schaechter, M.; Engleberg, N. C.; DiRita, V. J. et al. Schaechter’s Mechanisms of Microbial Disease. Hagerstown, MD: Lippincott Williams & Wilkins. p. 28.
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