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- RIP kinase
- DGY-06-116
DGY-06-116
DGY-06-116 is an irreversible covalent and selective inhibitor of Src with IC50 of 2.6 nM.
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包装价格促销价数量
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5mg￥1300.001040.00- +
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10mg￥2175.001740.00- +
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25mg￥4200.003360.00- +
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50mg￥6475.005180.00- +
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100mg￥9712.007770.00- +
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- 货号: ajcx33066
- CAS: 2556836-50-9
- 别名:
- 分子式: C32H33ClN8O2
- 分子量: 597.11
- 纯度: ＞98%
- 溶解度: DMSO : 250 mg/mL (418.68 mM; Need ultrasonic)
- 储存: Store at -20°C
- 库存: 现货
Background
DGY-06-116 is an irreversible covalent and selective inhibitor of Src with IC50 of 2.6 nM.
DGY-06-116 inhibits Src enzymatic activity. DGY-06-116 binds covalently to Src in a manner similar to SM1-71, where the p-loop must kink to establish the covalent bond.[1]
[1] Deepak Gurbani, et al. Front Mol Biosci. 2020 May 19;7:81.
