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  • ARV-110
ARV-110的可视化放大

ARV-110

Bavdegalutamide (ARV-110) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR. ARV-110 completely degrades androgen receptor (AR) in all cell lines tested with DC50 of < 1 nM. ARV-1

原价
￥1225-8362
价格
￥ 980-6690
ARV-110的二维码

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  • 库存: 现货
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  • 货号: ajcx33088
  • CAS: 2222112-77-6
  • 别名: ARV-110
  • 分子式: C41H43ClFN9O6
  • 分子量: 812.29
  • 纯度: >98%
  • 溶解度: DMSO : 26.67 mg/mL (32.83 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 80°C)
  • 储存: Store at-20°C, away from moisture
  • 库存: 现货

Background

Bavdegalutamide (ARV-110) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR. ARV-110 completely degrades androgen receptor (AR) in all cell lines tested with DC50 of < 1 nM. ARV-110 can be used for the research of prostate cancer.


[1] Taavi Neklesa, et al. Cancer Res 2018;78(13 Suppl):Abstract nr 5236.

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