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  • AT-511
AT-511的可视化放大

AT-511

A prodrug form of AT-9010

原价
¥3262-17625
价格
2610-14100
AT-511的二维码

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  • 库存: 现货
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  • 货号: ajcx33488
  • CAS: 1998705-64-8
  • 别名: AT-511
  • 分子式: C24H33FN7O7P
  • 分子量: 581.53
  • 纯度: >98%
  • 溶解度: DMSO : 100 mg/mL (171.96 mM; Need ultrasonic)
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

AT-511 is a prodrug form of the antiviral nucleoside analog AT-9010.1 It reduces the infectious virus yield in cells infected with Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome CoV (SARS-CoV), SARS-CoV-2, human CoV 229E (HCoV-229E), and HCoV-OC43 (EC90s = 37, 0.47, 2.8, 1.2, and 0.5 ?M, respectively).


1.Good, S.S., Westover, J., Jung, K.H., et al.AT-527, a double prodrug of a guanosine nucleotide analog, is a potent inhibitor of SARS-CoV-2 in vitro and a promising oral antiviral for treatment of COVID-19Antimicrob. Agents Chemother.65(4)e02479-02420(2021)

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