Tuberculosis inhibitor 3

Tuberculosis inhibitor 3 (compound 2i) 对敏感性，和耐性的MTB 菌株均具有良好的抗结核活性。Tuberculosis inhibitor 3 (compound 2i) 显示出良好的药代活性和口服生物利用度。

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库存: 现货

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5mg

￥2175.00

1740.00

- +
10mg

￥3487.00

2790.00

- +
25mg

￥7012.00

5610.00

- +
50mg

￥10575.00

8460.00

- +
100mg

￥15487.00

12390.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajcx33678
CAS: 2219325-28-5
别名:
分子式: C21H22F6N4O3S
分子量: 524.48
纯度: >98%
溶解度: DMSO : 27.5 mg/mL (52.43 mM; Need ultrasonic)
储存: Store at -20°C
库存: 现货

Background

Tuberculosis inhibitor 3 (compound 2i) displays potent anti-TB activity (MIC < 0.016 µg/mL) against drug-sensitive/resistant MTB strains. Tuberculosis inhibitor 3 (compound 2i) shows acceptable PK profiles with oral bioavailability[1].

Tuberculosis inhibitor 3 (compound 2i, 50 mg/kg) shows acceptable PK properties with the AUC of 2489 h?ng/mL) is. The Tmax of Tuberculosis inhibitor 3 is 0.25 h[1].

[1]. Kai Lv, et al. Design, synthesis and antitubercular evaluation of benzothiazinones containing a piperidine moiety. Eur J Med Chem. 2018 May 10;151:1-8.