SRX3207的可视化放大

SRX3207

SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively. SRX3207 blocks tumor immunosuppression and inc

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库存: 现货

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包装

价格

促销价

数量
5mg

￥4312.00

3450.00

- +
10mg

￥7337.00

5870.00

- +
25mg

￥14425.00

11540.00

- +
50mg

￥23512.00

18810.00

- +
100mg

￥36337.00

29070.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajcx33758
CAS: 2254693-15-5
别名:
分子式: C29H29N7O3S
分子量: 555.65
纯度: ＞98%
溶解度: DMSO : 5 mg/mL (9.00 mM; Need ultrasonic)
储存: Store at -20°C
库存: 现货

Background

SRX3207 is an orally active dual inhibitor of Syk-PI3K with IC50 of 39.9 nM, 31200 nM, 3070 nM, 3070 nM, 244 nM, 388 nM, 9790 nM for Syk, Zap70, BRD41, BRD42, PI3K alpha, PI3K delta, PI3K gamma, respectively. SRX3207 blocks tumor immunosuppression and increases anti-tumor immunity.

SRX3207 blocks both PI3K and Syk in MΦs thereby activating innate and adaptive antitumor immunity in vivo.[1]

[1] Shweta Joshi, et al. Mol Cancer Ther . 2020 Mar;19(3):755-764.

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