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  • (Rac)-Hesperetin
(Rac)-Hesperetin的可视化放大

(Rac)-Hesperetin

(Rac)-Hesperetin 是Hesperetin 的外消旋体。 Hesperetin 是一种天然黄烷酮类物质,为有效的,广谱的人 UGT 抑制剂。Hesperetin 可通过激活 p38 MAPK 来诱导凋亡。

原价
¥550-550
价格
440-440
(Rac)-Hesperetin的二维码

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  • 货号: ajcx33900
  • CAS: 69097-99-0
  • 别名: 3′,5,7-三羟基-4-甲氧基黄酮
  • 分子式: C16H14O6
  • 分子量: 302.28
  • 纯度: >98%
  • 溶解度: DMSO : 125 mg/mL (413.52 mM; Need ultrasonic)
  • 储存: Store at -20°C
  • 库存: 现货

Background

(Rac)-Hesperetin is the racemate of Hesperetin. Hesperetin is a natural flavanone, and acts as a potent and broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation.


[1]. Arya A, et al. Bioflavonoid hesperetin overcome bicalutamide induced toxicity by co-delivery in novel SNEDDS formulations: Optimization, in vivo evaluation and uptake mechanism. Mater Sci Eng C Mater Biol Appl. 2017 Feb 1;71:954-964
[2]. Liu D, et al. Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions. Biol Pharm Bull. 2016;39(12):2052-2059.
[3]. Shagirtha K, et al. Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats. Toxicol Ind Health. 2016 Nov 1. pii: 0748233716665301
[4]. Li Q, et al. Hesperetin Induces Apoptosis in Human Glioblastoma Cells via p38 MAPK Activation. Nutr Cancer. 2019 Jul 11:1-8.

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