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- (S)-Higenamine hydrobromide
(S)-Higenamine hydrobromide
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide，Higenamine 的 S 型异构体，是苄基异喹啉生物碱生物合成的起始化合物，由去甲月桂碱合酶 (NCS) 将多巴胺和 4-羟基苯乙醛 (4-HPAA) 缩合生成。
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包装价格促销价数量
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1mg￥4525.003620.00- +
- 货号: ajcx34344
- CAS: 105990-27-0
- 别名: (S)-(-)-去甲乌药碱氢溴酸盐,(S)-Norcoclaurine hydrobromide
- 分子式: C16H18BrNO3
- 分子量: 352.22
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].
The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].
[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.
