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- 7-Methylguanosine 5’-diphosphate sodium
7-Methylguanosine 5’-diphosphate sodium
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium，一种 cap 类似物，可以用来合成 mRNA cap 类似物。
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包装价格促销价数量
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1mg￥1787.001430.00- +
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5mg￥5337.004270.00- +
- 货号: ajcx34470
- CAS: 104809-16-7
- 别名: 7-Methyl-GDP sodium; m7GDP sodium
- 分子式: C11H16N5NaO11P2
- 分子量: 479.21
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].
7-Methylguanosine 5’-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5’-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].
[1]. Sonenberg N, et al. Nonspecific effect of m7GMP on protein-RNA interactions. J Biol Chem. 1978;253(19):6630-6632.
[2]. Ignatochkina AV, et al. The messenger RNA decapping and recapping pathway in Trypanosoma. Proc Natl Acad Sci U S A. 2015;112(22):6967-6972.
