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- HSP (Heat shock proteins)
- Araloside C
Araloside C
Araloside C 对心肌缺血/再灌注损伤具有保护作用。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
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包装价格促销价数量
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1mg￥5175.004140.00- +
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5mg￥14962.0011970.00- +
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10mg￥30450.0024360.00- +
- 货号: ajcx34528
- CAS: 55446-15-6
- 别名: 楤木皂苷C
- 分子式: C53H84O23
- 分子量: 1089.22
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
Araloside C exhibits protective effects against myocardial ischaemia/reperfusion injury[1].
Araloside C also up-regulates the expression levels of Hsp90 and improved cell viability in hypoxia/reoxygenation-treated H9c2 cardiomyocytes, whereas the addition of 17-AAG, a pharmacologic inhibitor of Hsp90, attenuates Araloside C-induced cardioprotective effect[1].Araloside C (0.5-2.5 μM) concentration-dependently improves the functional recovery of the I/R hearts, including increase in the recovery of LVDP, dP/dtmax and heart rate throughout the reperfusion period, although the baseline mechanical parameters with Araloside C were not significantly different compared with those of the control condition[1].Araloside C could improve post-ischaemic cell shortening and Ca2+ transients from 2 to 8 μM[1].
[1]. Min Wang, et al. Protective effects of Araloside C against myocardial ischaemia/reperfusion injury: potential involvement of heat shock protein 90. J Cell Mol Med. 2017 Sep;21(9):1870-1880.
