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- Janus kinase (JAK)
- Coumermycin A1
Coumermycin A1
Coumermycin A1 是一种 JAK2 信号激活剂。Coumermycin A1 抑制 DNA 旋转酶 (DNA Gyrase)，从而抑制细菌的细胞分裂。
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5mg￥7012.005610.00- +
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- 货号: ajcx34644
- CAS: 4434-05-3
- 别名: 香豆霉素
- 分子式: C55H59N5O20
- 分子量: 1110.08
- 纯度: ＞98%
- 溶解度: DMSO : 50 mg/mL (45.04 mM; Need ultrasonic and warming)
- 储存: Store at -20°C
- 库存: 现货
Background
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria.
Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea leptin receptor mRNA level[1].
[1]. Tiantian Zhang, et al. SOCS2 Inhibits Mitochondrial Fatty Acid Oxidation via Suppressing LepR/JAK2/AMPK Signaling Pathway in Mouse Adipocytes. Research Article.
