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Diadenosine pentaphosphate pentaammonium 是一种内源性血管活性嘌呤二核苷酸,可从血小板中分离出来。Diadenosine polyphosphates (ApnA, n=2-7) 已被确定为分泌小泡的成分,如血小板、嗜铬细胞、Torpedo 突出末端和脑突触体。
Diadenosine pentaphosphate pentaammonium is an endogenous vasoactive purine dinucleotide which has been isolated from thrombocytes. Diadenosine polyphosphates (ApnA, n=2-7) have been identified as constituents of secretory vesicles such as in platelets, chromaffin cells, Torpedo synaptic terminals and brain synaptosomes[1][2].
[1]. L Giraldez, et al. Adenosine triphosphate and diadenosine pentaphosphate induce [Ca(2+)](i) increase in rat basal ganglia aminergic terminals. J Neurosci Res. 2001 Apr 15;64(2):174-82.
[2]. Jesús Pintor, et al. Presence of diadenosine polyphosphates in human tears. Pflugers Arch. 2002 Jan;443(3):432-6.
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