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MBD的可视化放大

MBD

MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole),一种新的蛋白质和核蛋白构象荧光探针,可用于细菌核糖体、牛胰蛋白酶原和胰蛋白酶。MBD 在与大分子的疏水区域结合时具有强荧光性。

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MBD的二维码
  • 库存: 现货
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  • 100mg
    ¥1037.00
    830.00
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  • 货号: ajcx34944
  • CAS: 33984-50-8
  • 别名: 4-(对甲氧基苄氨基)-7-硝基-2,1,3-苯并噁二唑,7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole
  • 分子式: C14H12N4O4
  • 分子量: 300.27
  • 纯度: >98%
  • 溶解度:
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule[1][2].


[1]. Kenner RA, et al. A new fluorescent probe for protein and nucleoprotein conformation. Binding of 7-(p-methoxybenzylamino)-4-nitrobenzoxadiazole to bovine trypsinogen and bacterial ribosomes. Biochemistry. 1971;10(24):4433-4440.
[2]. Kasahara Y, et al. Formation of a conformationally changed C1r, a subcomponent of the first component of human complement, as an intermediate of its autoactivation reaction. FEBS Lett. 1982;141(1):128-131.

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