MYF-01-37

MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with the TEAD2 protein.

原价

￥762-7012

价格

￥ 610-5610

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产品引用

货号: ajcx34996
CAS: 2416417-65-5
别名:
分子式: C15H17F3N2O
分子量: 298.3
纯度: >98%
溶解度: DMSO : 250 mg/mL (838.08 mM; Need ultrasonic)
储存: Store at -20°C
库存: 现货

Background

MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with the TEAD2 protein.

MYF-01-37 is developed as a covalent binder to TEAD, targeting Cys380 when incubated with the TEAD2 protein (C359 in TEAD1). Pretreating cells with MYF-01-37 leads to loss of direct TEAD pull-down by biotin-MYF-01-037 from whole-cell lysate, confirming MYF-01-037 binding to TEAD in cells.[1]

[1] Kari J Kurppa, et al. Cancer Cell. 2020 Jan 13;37(1):104-122.e12.

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生命科学

有机化学

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材料科学

MYF-01-37

MYF-01-37详情

Background