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Tesirine (SG3249) 是一种用于抗体偶联药物 (ADC) 的 药物-linker 连接物,能用于多种癌症的研究。PBD Dimer 是一种 DNA 烷化剂,能抑制 DNA 复制。
Tesirine (SG3249) is a drug-linker conjugates for ADC which is used in the treatment of several cancers. PBD Dimer is a DNA alkylating which inhibits DNA replication[1].
[1]. Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs. Uppsala Universitet.
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