Toltrazuril sulfoxide 是托曲脲短暂的中间代谢物 (intermediary metabolite)，在体内可代谢为活性的托曲脲砜 (TZR-SO2)。Toltrazuril 是一种抗原生动物 (antiprotozoal agent) 试剂，作用于 Coccidia 球虫寄生虫。
Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril , and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites[1].
[1]. Jong-Hwan Lim, et al. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72(8):1085-7. [2]. H Mehlhorn, et al. Toltrazuril effective against a broad spectrum of protozoan parasites. Parasitol Res. 1988;75(1):64-6.
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