DP-1 是 SDC-TRAP-0063 的降解产物,是 Ganetespib 的一个片段。Ganetespib 是一种具有抗肿瘤活性的热休克蛋白 90 (HSP90) 抑制剂。
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DP-1, a degradation product of SDC-TRAP-0063, is a fragment of Ganetespib. Ganetespib is a heat shock protein 90 (HSP90) inhibitor with anti-tumor activity[1].
DP-1 is the SDC-TRAP-0063 degradation product which can be found in plasma, tumor and heart[1].
[1]. Chimmanamada DU, et, al. Targeted therapeutics. US20140079636A1.