- 首页
- Angiotensin-converting Enzyme (ACE)
- AT-9010 tetrasodium
AT-9010 tetrasodium
AT-9010 tetrasodium 是 AT-527 的三磷酸活性代谢物，是一种有效的 NiRAN (病毒复制必不可少的功能) 的抑制剂。AT-9010 tetrasodium 可以抑制 SARS-CoV-2 的复制。
此产品仅用于科学研究，我们不为任何个人用途提供产品和服务
-
包装价格促销价数量
-
1mg￥11662.009330.00- +
-
5mg￥28312.0022650.00- +
已选
0
种
0
瓶
金额:
￥0.00
首页
收藏
- 货号: ajcx35628
- CAS: 1621884-18-1
- 别名:
- 分子式: C11H13FN5Na4O13P3
- 分子量: 627.13
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -80°C,protect from light, stored under nitrogen
- 库存: 现货
Background
AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 tetrasodium can inhibit SARS-CoV-2 replication[1].
Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.
