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- Janus kinase (JAK)
- Itacnosertib
Itacnosertib
Itacnosertib (TP-0184) 是JAK2，ACVR1 (ALK2)和ALK5的抑制剂，如WO2014151871所述。
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包装价格促销价数量
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10mM*1mL￥3362.002690.00- +
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5mg￥3262.002610.00- +
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10mg￥5175.004140.00- +
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25mg￥10250.008200.00- +
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50mg￥15487.0012390.00- +
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- 货号: ajcx35636
- CAS: 1628870-27-8
- 别名: TP-0184
- 分子式: C26H28N8O
- 分子量: 468.55
- 纯度: ＞98%
- 溶解度: DMSO : 12.5 mg/mL (26.68 mM; ultrasonic and warming and heat to 60°C)
- 储存: Store at -20°C
- 库存: 现货
Background
Itacnosertib (TP-0184) is both inhibitor to JAK2, ACVR1 (ALK2) and ALK5 as described in WO2014151871[1].
[1]. Mollard, Alexis; Warner, Steven L.; Flynn, Gary A.; Vankayalapati, Hariprasad; Bearss, David J. Preparation of [(piperazinylphenyl)amino]pyrimidine derivatives as JAK2 and ALK2 inhibitors. WO2014151871 A2
