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Eclitasertib (DNL-758) 是一种受体相互作用蛋白激酶1 (RIPK1) 抑制剂,IC50 值为 <1 µμ(来自专利WO2017136727A2,example 42)。
Eclitasertib (DNL-758) is a potent receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC50 of <1 µμ (From patent WO2017136727A2, example 42)[1].
[1]. Anthony A. ESTRADA, et al. Compounds, compositions and methods. WO2017136727A2.
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