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  • HM43239
HM43239的可视化放大

HM43239

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM,

原价
￥6900-13675
价格
￥ 5520-10940
HM43239的二维码

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  • 库存: 现货
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  • 货号: ajcx35818
  • CAS: 2294874-49-8;2569527-64-4
  • 别名: HM43239
  • 分子式: C29H33ClN6
  • 分子量: 501.07
  • 纯度: >98%
  • 溶解度: DMSO : 125 mg/mL (249.47 mM; Need ultrasonic)
  • 储存: 4°C, protect from light
  • 库存: 现货

Background

HM43239 is a novel potent small molecule FLT3 inhibitor that selectively inhibits not only FLT3 wild type, ITD mutants or TKD mutations, but also FLT3 ITD/TKD double mutations. IC50s' of HM43239 against FLT3 WT, FLT3 ITD and FLT3 D835Y kinases are 1.1 nM, 1.8 nM and 1.0 nM, respectively.


[1] Miyoung Lee, et al. Cancer Research AM2018-804 Published July 2018.

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