Cycloposine 是一种甾体生物碱，存在于 Veratrum californicum 的根和根茎中。Cycloposine 也是一种致畸化合物。
Cycloposine is a steroidal alkaloid that can be found in the roots and rhizomes of Veratrum californicum. Cycloposine is also a teratogenic compound[1].
Cycloposine producs fetal cyclopia and related central nervous system malformations in sheep[2].
[1]. Chandler CM, et, al. Improved extraction and complete mass spectral characterization of steroidal alkaloids from Veratrum californicum. Nat Prod Commun. 2013 Aug;8(8):1059-64.
[2]. Keeler RF. Teratogenic compounds of Veratrum californicum (Durand). VII. The structure of the glycosidic alkaloid cycloposine. Steroids. 1969 May;13(5):579-88.
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