Benzamide-15N
Benzamide-15N (NSC-3114-15N) 是一种 15N 标记的 Benzamide. Benzamide 可抑制 poly(ADP-ribose) polymerase (PARP).
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包装价格促销价数量
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5mg￥325.00260.00- +
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10mg￥550.00440.00- +
- 货号: ajcx35954
- CAS: 31656-62-9
- 别名: 苯甲酰胺-15N,Benzenecarboxamide-15N; Phenylamide-15N
- 分子式: C7H7 15NO
- 分子量: 122.13
- 纯度: ＞98%
- 溶解度:
- 储存: Store at -20°C
- 库存: 现货
Background
Benzamide-15N (NSC-3114-15N) is a 15N-labeled Benzamide. Benzamide inhibits poly(ADP-ribose) polymerase (PARP)[1][2].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Cosi C, et al. Benzamide, an inhibitor of poly(ADP-ribose) polymerase, attenuates methamphetamine-induced dopamine neurotoxicity in the C57B1/6N mouse. Brain Res. 1996;735(2):343-348.
