Dimethyl phthalate-d6 是 Dimethyl phthalate 的氘代物。Dimethyl phthalate,一种已知的内分泌干扰物,也是一种邻苯二甲酸酯 (PAEs),也是一种普遍存在的污染物。Dimethyl phthalate 通常用作增塑剂,赋予硬质聚氯乙烯 (PVC) 树脂以柔韧性。
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Dimethyl phthalate-d6 is the deuterium labeled Dimethyl phthalate. Dimethyl phthalate, a known endocrine disruptor and one of the phthalate esters (PAEs), is a ubiquitous pollutant. Dimethyl phthalate is commonly used as a plasticizer to impart flexibility to rigid polyvinylchloride (PVC) resins[1].
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Wang ZG, et al. Impacts of dimethyl phthalate on the bacterial community and functions in black soils. Front Microbiol. 2015 May 5;6:405.
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