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Dydrogesterone-D6 是 Dydrogesterone 的氘代物。Dydrogesterone 是口服活性的孕激素,可作用于孕酮缺乏相关疾病。
Dydrogesterone-D6 is the deuterium labeled Dydrogesterone. Dydrogesterone is a potent, orally active progestogen indicated in a wide variety of gynaecological conditions related to progesterone deficiency.
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Dydrogesterone, From Wikipedia, the free encyclopedia
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