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  • Histone H2A (1-20)
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Histone H2A (1-20)

A peptide fragment of histone H2A

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  • 货号: ajcx36314
  • CAS: N/A
  • 别名:
  • 分子式: C83H155N37O26
  • 分子量: 2087.4
  • 纯度: >98%
  • 溶解度: Water : 100 mg/mL (47.91 mM; Need ultrasonic)
  • 储存: Store at -20°C
  • 库存: 现货

Background

Histone H2A (1-20) is an N-terminal peptide fragment of histone H2A that corresponds to amino acid residues 2-21 of the human histone H2A sequence. Methylation of the arginine at position 3 of histone H2A by protein arginine methyltransferase 1 (PRMT1), PRMT5, or PRMT6 is associated with both transcriptional activation and repression.1 It is associated with DNA damage repair when methylated by PRMT7. The arginine residue at position 3 of histone H2A is also subject to citrullination by protein arginine deiminase 4 (PAD4).


1.Fuhrmann, J., and Thompson, P.R.Protein arginine methylation and citrullination in epigenetic regulationACS Chem. Biol.11(3)654-668(2016)

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