现货大促销,价格低至8折起,量大更优惠,详细咨询客服
全部分类
全部分类
  • Dihydroergotoxine mesylate
Dihydroergotoxine mesylate的可视化放大

Dihydroergotoxine mesylate

A mixture of alkaloids with diverse biological activities

原价
¥900-900
价格
720-720
Dihydroergotoxine mesylate的二维码

所有产品仅用于科学研究,我们不为任何个人用途提供产品和服务

询价有惊喜,量大更优惠 点击这里给我发消息

  • 库存: 现货
可选包装 >>>
首页
  • 货号: ajci5302
  • CAS: 8067-24-1
  • 别名: 甲磺酸二氢麦角碱; Ergoloid mesylates
  • 分子式: C20H29N3O5S
  • 分子量: 423.53
  • 纯度: >98%
  • 溶解度: DMSO: Slightly Soluble,Methanol: 1 mg/ml
  • 储存: Store at RT
  • 库存: 现货

Background

Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site.IC50 value:Target: Dihydroergotoxine mesylate also interacts with central dopaminergic, serotonergic and adrenergic (α1) receptors. Dihydroergotoxine mesylate displays antiproliferative activity in vitro (IC50 = 18 - 38 μM in prostate cancer cells) and exhibits cognition-enhancing, anticonvulsant and sedative activity in vivo.


参考文献:
[1]. Tvrdeic A, et al. Dihydrogenated ergot compounds bind with high affinity to GABAA receptor-associated Cl- ionophore. Eur J Pharmacol. 1991 Sep 4;202(1):109-11.
[2]. Tvrdeic A, et al. Dihydroergotoxine modulation of the GABAA receptor-associated Cl- ionophore in mouse brain. Eur J Pharmacol. 1992 Oct 6;221(1):139-43.
[3]. Tvrdeic A, et al. Effect of ergot alkaloids on 3H-flunitrazepam binding to mouse brain GABAA receptors. Coll Antropol. 2003;27 Suppl 1:175-82.
[4]. Abdul M, et al. Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer. Acta Oncol. 2008;47(8):1546-50.

动态评分

0.0

没有评分数据
没有评价数据
一键回到顶部
展开 收缩
安捷凯在线客服