Tenidap

A COX-1 selective NSAID

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库存: 现货

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促销价

数量
1mg

￥537.00

430.00

- +
5mg

￥1175.00

940.00

- +
10mg

￥2062.00

1650.00

- +

已选 0 种 0 瓶

金额: ￥0.00

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货号: ajci7948
CAS: 120210-48-2
别名: 替尼达普,CP-66248
分子式: C14H9N2O3SCl
分子量: 320.75
纯度: >98%
溶解度: DMF: 10 mg/ml,DMSO: 20 mg/ml,Ethanol: slightly soluble
储存: Store at -20°C
库存: 现货

Background

Tenidap, a non-steroidal anti-inflammatory drug, is a selective COX-1 inhibitor, with IC50 values of 0.03 μM and 1.2 μM for COX-1 and COX-2, respectively. Tenidap has anti-inflammatory and antirheumatic properties[1][2]. Tenidap is also a specific SLC26A3 inhibitor.

参考文献:
[1]. Kirchner T, et al. Evaluation of the antiinflammatory activity of a dual cyclooxygenase-2 selective/5-lipoxygenase inhibitor, RWJ 63556, in a canine model of inflammation. J Pharmacol Exp Ther. 1997 Aug;282(2):1094-101.
[2]. Blackburn WD Jr, et al. Tenidap in rheumatoid arthritis. A 24-week double-blind comparison with hydroxychloroquine-plus-piroxicam, and piroxicam alone. Arthritis Rheum. 1995 Oct;38(10):1447-56.