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MRE 3008F20 是一种高效、高选择性的放射性腺苷 A3 受体 (AA3R) 拮抗剂 (Ki\u003d1.8 nM)。
MRE3008F20 is a highly potent and selective antagonist of adenosine A3 receptor (AA3R), inhibits agonist-induced cAMP elevation in resting T lymphocytes with an IC50 of 5 nM[1].
参考文献:
[1]. Gessi S, et al. Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation. Mol Pharmacol. 2004 Mar;65(3):711-9.
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