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  • Doramectin
Doramectin的可视化放大

Doramectin

An anthelmintic antibiotic

原价
¥375-662
价格
300-530
Doramectin的二维码

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  • 货号: ajci9802
  • CAS: 117704-25-3
  • 别名: 多拉菌素
  • 分子式: C50H74O14
  • 分子量: 899.11
  • 纯度: >98%
  • 溶解度: ≥ 89.9 mg/mL in DMSO, ≥ 14.43 mg/mL in EtOH with gentle warming
  • 储存: -20°C, protect from light
  • 库存: 现货

Background

Doramectin is an antiparasitic agent.IC50 Value:Target: AntiparasiticDoramectin (Dectomax) is a veterinary drug approved by the Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in cattle. Mutational biosynthetic antiparasitic antibiotic structurally related to the avermectins.


参考文献:
[1]. Davey RB, Pound JM, Klavons JA, Lohmeyer KH, Freeman JM, Olafson PU.Analysis of doramectin in the serum of repeatedly treated pastured cattle used to predict the probability of cattle fever ticks (Acari: Ixodidae) feeding to repletion.Exp Appl Acarol. 2012 Apr;56(4):365-74. doi: 10.1007/s10493-012-9525-1.
[2]. Wang XJ, Zhang J, Wang JD, Huang SX, Chen YH, Liu CX, Xiang WS.Four new doramectin congeners with acaricidal and insecticidal activity from Streptomyces avermitilis NEAU1069.Chem Biodivers. 2011 Nov;8(11):2117-25. doi: 10.1002/cbdv.201000295.
[3]. Sarre C, Claerebout E, Vercruysse J, Levecke B, Geldhof P, Pardon B, Alvinerie M, Sutra JF, Geurden T.Doramectin resistance in Haemonchus contortus on an alpaca farm in Belgium.Vet Parasitol. 2012 Apr 30;185(2-4):346-51.
[4]. Lobetti R..Successful resolution of oesophageal spirocercosis in 20 dogs following daily treatment with oral doramectin.Vet J. 2012 Jul;193(1):277-8.
[5]. Wang JB, Pan HX, Tang GL.Production of doramectin by rational engineering of the avermectin biosynthetic pathway.Bioorg Med Chem Lett. 2011 Jun 1;21(11):3320-3.

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