Oleamide

An amide of oleic acid and agonist of CB1 receptors

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
50mg

￥1962.00

1570.00

- +
10mg

￥1087.00

870.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci12326
CAS: 301-02-0
别名: 油酸酰胺
分子式: C18H35NO
分子量: 281.48
纯度: >98%
溶解度: DMF: >14 mg/ml (from 13-Docosenamid,DMSO: >20 mg/ml (from 13-Docosenamid,Ethanol: >22 mg/ml (from 13-Docosenamid,PBS pH 7.2: <50 μ g/ml (from 13-Docosenamid
储存: Store at -20°C
库存: 现货

Background

Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.

Oleamide accumulates in the cerebrospinal fluid (CSF) of rats after six hours of sleep deprivation and induces sleep in naive rats and mice. Inhibition of the primary catabolic enzyme of oleamide (fatty acid amide hydrolase) by trifluoromethyl-octadecenone reduces sleep latency and increases total sleep time when given centrally to rats and peripherally to mice[1]

参考文献:
[1]. Mendelson WB, et al. The hypnotic actions of the fatty acid amide, oleamide. Neuropsychopharmacology. 2001 Nov;25(5 Suppl):S36-9.