Moxalactam (sodium salt)

A β-lactam antibiotic

此产品仅用于科学研究，我们不为任何个人用途提供产品和服务

库存: 现货

可选规格

包装

价格

促销价

数量
250mg

￥437.00

350.00

- +
500mg

￥775.00

620.00

- +
1g

￥1262.00

1010.00

- +

已选 0 种 0 瓶

金额: ￥0.00

首页收藏

货号: ajci13024
CAS: 64953-12-4
别名: 拉氧头孢钠; Latamoxef sodium; Lamoxactam sodium; LY-127935 sodium
分子式: C20H18N6O9S ? 2Na
分子量: 564.4
纯度: >98%
溶解度: ≥ 25.95mg/mL in DMSO
储存: Store at -20°C
库存: 现货

Background

Moxalactam (sodium salt) is a β-lactam antibiotic.

β-lactam antibiotics (beta-lactam antibiotics) are a class of broad-spectrum antibiotics that contain a beta-lactam ring in their molecular structures. Most β-lactam antibiotics act by inhibiting cell wall biosynthesis.

Moxalactam is an oxacephem antibiotic and inhibits most commonly occurring gram positive, gram negative, and anaerobic bacteria. Moxalactam was more active against Klebsiella and E coli than cefoperazone. Moxalactam did not inhibit methicillin-resistant S. aureus and Enterococci. Moxalactam had been extremely active against Haemophilis and Neisseria gonorrhoeae. Moxalactam was extremely resistant to hydrolysis by all plasmid and chromosmal β-lactamases [1]. In certain situations, Moxalactam impaired normal hemostasis and prolonged bleeding time [2].

参考文献:
[1].? Neu HC. The in vitro activity, human pharmacology, and clinical effectiveness of new beta-lactam antibiotics. Annu Rev Pharmacol Toxicol. 1982;22:599-642.
[2].? Sattler FR, Weitekamp MR, Ballard JO. Potential for bleeding with the new beta-lactam antibiotics. Ann Intern Med. 1986 Dec;105(6):924-31.