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An NSAID and a class IIb HDAC inhibitor
Bufexamac is a class IIB histone deacetylases (HDAC6 and HDAC10) inhibitor used as an anti-inflammatory agent.
参考文献:
[1]. Bantscheff, M., et al., Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol, 2011. 29(3): p. 255-65.
[2]. Kranke, B., et al., Epidemiological significance of bufexamac as a frequent and relevant contact sensitizer. Contact Dermatitis, 1997. 36(4): p. 212-5.
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